Microneedling with PRP

Microneedling is a noninvasive procedure whereby micro needles are used to reduce fine lines and wrinkles and tighten skin. The micro needle stimulates collagen production in the skin without damaging the skin. When microneedling is combined with PRP, the therapy may then be referred to as a "vampire facial" or "collagen induction therapy".

Microneedling with PRP Overview - Everything You Need to Know

The Skinny

Microneedling with PRP
avg. recovery
5 days
Mechanical Abrasion
$700 - $4500

About the Procedure

Last Updated: 08.05.2021

Microneedling procedures can be combined with a variety of other treatments and serums to provide maximum effectiveness of the benefits of the collagen inducing micro-injuries caused during the procedure. Microneedling with PRP is a popular variation of the treatment as well as the addition of a stem cell based serum, sometimes referred to as Trifecta Therapy. The process for microneedling with PRP begins with the collection of blood to make the PRP. First, blood will be drawn from a vein in the arm, typically 5-15mL. The blood sample is then placed in a centrifuge which isolates the platelets, forming the platelet-rich plasma (PRP) concentration. This step in the process typically takes 15 minutes. While the centrifuge is distilling the PRP, the patient’s skin will be cleansed in preparation for the treatment. A light numbing agent will be applied to the treatment area to help prevent discomfort during the procedure. The practitioner will gently glide the microneedling device over the area to be treated, creating tiny holes in the skin penetrating approximately .5 to 2mm in depth. The microneedling device is a hand held machine that will have between 12-80 sterile, stainless needles that penetrate the skin. The depth and number of needles on a device will depend on the brand used by the practitioner. Once the area has been thoroughly treated, the practitioner will then apply the now developed PRP concentration. Skin will begin to feel taut shortly after the session. Following treatment it is advised to not wash off any residual residue so as to allow the PRP to continue to penetrate the skin. Skin will progressively improve in the weeks to come in tone and texture.

The goal of a microneedling and PRP procedure is to target imperfections of the skin with micro-injuries which cause the release of growth factors and triggers the wound healing process, thereby producing collagen and creating younger looking skin.

Recovery Notes

For at least 2 hours post treatment, do not use any alpha hydroxy acids, beta hydroxy acid, retinol products, or vitamin C based skincare. Avoid direct sun exposure and tanning beds for 24 hours. Do not go swimming for at least 24 hours after your microneedling with PRP procedure. Avoid exercising and strenuous activity for the first 24 hours following treatment.

Ideal Candidate

Microneedling with PRP is ideal for someone that wishes to improve the appearance of minor skin imperfections such as fine lines and wrinkles, skin laxity, scarring, and uneven skin tone and texture.

Not Recommended For

Microneedling with PRP is not recommended for those who have used Accutane within six months, have open wounds or a skin infection, have had radiation treatment within the last year, are pregnant, or have a history of keloid scars.

Side Effects

Microneedling with PRP is generally well tolerated but erythema may be seen after treatment, lasting for 2-3 days. Skin may also feel warm, tight and itchy after treatment however this normally resolves in 12-48 hours. Sun protection is advised for a week and local antibiotic creams may be prescribed to help prevent a bacterial infection.


  • Noninvasive
  • Low risk of side effects


  • Temporary
  • Limited results
  • Multiple treatments needed

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