Trifecta Therapy

Trifecta Therapy is a facial rejuvenation procedure that combines microneedling, platelet rich plasma, and stem cell growth factor serum to smooth and tighten sagging skin. Microneedling stimulates collagen production while the PRP and stem cell serum add nutrients to the skin.

Trifecta Therapy Overview - Everything You Need to Know

The Skinny

Trifecta Therapy
avg. recovery
5 days
Mechanical Abrasion
$600 - $700

About the Procedure

Last Updated: 07.27.2021

Trifecta Therapy is a combination of treatments each designed to rejuvenate the skin, but done together to enhance results. Microneedling, platelet rich plasma, and stem cell serum are used during the procedure to smooth fine lines and plump the skin. The microneedling procedure is completed first to create hundreds of tiny microchannels within the treatment area. The platelet rich plasma, or PRP, and growth factor serum are applied immediately after to deeply penetrate the tissue for optimal results. Prior to treatment the skin will be cleansed to removed any makeup, oils, or lotions. A topical numbing cream will then be applied for optimal patient comfort. While the skin is being numbed, a small amount of blood will be collected from the patient and placed in a centrifuge to extract the PRP. Once the skin is completely numbed, the microneedling procedure will begin. Immediately following the microneedling, the PRP will be applied to the skin as well as the stem cell serum. The PRP and stem cell serum, which will appear clear on the skin, should be left on for the remainder of the day. Normal skin care routines can be resumed the day after treatment.

The goal of microneedling with PRP and stem cells is to assist in skin regeneration and tightening, pore reduction, scars, acne, mild wrinkles, and skin discoloration.

Recovery Notes

Most patients experience minor redness as well as skin dryness and shedding which are all expected. There is no downtime with microneedling with PRP and stem cells however if the procedure is being done in preparation for an event, it is advised to schedule treatment at least 1 week in advance to ensure adequate time for redness to dissipate.

Ideal Candidate

Microneedling with PRP and stem cells is ideal for someone that wishes to improve the appearance of minor skin imperfections such as fine lines and wrinkles, skin laxity, scarring, and uneven skin tone and texture. This technique is also very safe for darker skin tones in contrast to many other skin rejuvenation techniques.

Not Recommended For

Microneedling with PRP and stem cells is not recommended for those who have used Accutane within six months, have open wounds or a skin infection, have had radiation treatment within the last year, are pregnant, or have a history of keloid scars.

Side Effects

Microneedling with PRP and stem cells is generally well tolerated but erythema may be seen after treatment, lasting for 2-3 days. Skin may also feel warm, tight and itchy for a short while, which normally resolves after 12-48 hours. Treated skin may be more prone to hyperpigmentation so strict adherence to photoprotection is advised for a week after.


  • short recovery time
  • low risk of side effects
  • long lasting
  • skin tightening


  • limited results
  • multiple treatments needed

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