Belotero® by Merz Pharmaceuticals is a commercial injectable formulation of hyaluronic acid. Naturally occurring in the human body, hyaluronic acid is a compound that increases volume and plumpness for both cosmetic and functional purposes.

Belotero® Overview - Everything You Need to Know

The Skinny

avg. recovery
5 days
$250 - $1498

About the Procedure

Last Updated: 09.25.2021

Belotero® is an injectable temporary dermal filler by Merz Pharmaceuticals that is composed of hyaluronic acid (HA). Belotero® is approved by the United States Food and Drug Administration (FDA) to correct common cosmetic concerns including fine lines and wrinkles and chin, temple, and cheek-area definition. Hyaluronic acid fillers are the most popularly used dermal fillers in the U.S. and are well-studied for their safety and efficacy. Belotero® by Merz is a product line of injectable gel hyaluronic acid-based dermal fillers uniquely targeted to a specific cosmetic concern and treatment area: - Belotero® Soft for perioral (a.k.a. smoker) lines - Belotero® Balance for moderate perioral lines, nasolabial folds, marionette lines, lips, and the oral commissures - Belotero® Intense for deep nasolabial folds and oral commissures, and marionette folds - Belotero® Volume for cheeks, temples, and chin - Belotero® Lips for lip shape and contour - Belotero® Revive the newest HA formulation for fine lines Hyaluronic acid is a naturally occurring compound produced in nature and by the human body. Hyaluronic acid pulls water into the injected area to increase volume and plumpness, smooth fine lines and wrinkles, and stimulate the body’s own collagen production. Hyaluronic acid is considered the most temporary of the dermal fillers. For those seeking more lasting results, alternative products such as Radiesse®, Sculptra®, and Bellafill® may be considered.

The goal of hyaluronic acid-based fillers is the temporarily improve the volume and/or contour of areas on the face and body.

Recovery Notes

Most individual candidates experience minimal recovery with swelling, tenderness, and redness at the injection site lasting about 24 hours. For some patients, swelling may persist for a few days. Many resume almost all normal activities directly following the injections.

Ideal Candidate

The ideal candidate for Belotero® injections is over 18 years old and looking for a proven effective temporary solution to common facial cosmetic concerns.

Not Recommended For

Belotero® is not recommended for women who are pregnant or nursing, anyone with an allergy to the components of Belotero®, proclivity to scarring and skin inflammation, and those with certain immunologic disorders.

Side Effects

Common side effects of Belotero® injections are redness, dryness, and flaking. Firmess, tenderness, itchiness, lumps, bumps, possible site infection, and/or bruising and discoloration may occur. A serious complication of a Belotero® injection is intravascular injection (injection into a blood vessel) leading to skin necrosis. Severe allergic reactions can occur.


  • Immediate results
  • Minimally invasive
  • Reversible with hyaluronidase


  • Temporary results
  • Possible asymmetry
  • Reoccurring expense