Iontophoresis for Hyperhidrosis

Iontophoresis is a minimally invasive treatment for hyperhidrosis that can be performed in-office or at home.

Iontophoresis for Hyperhidrosis Overview - 1188

The Skinny

Average Recovery

1 days




Thermal Treatment




$100 - $150

The Specifics

What is iontophoresis?

Iontophoresis is a non-invasive thermal therapy used in the treatment of palmoplantar hyperhidrosis or axillary hyperhidrosis. Iontophoresis works by using direct current to alter skin, nerves, and sweat glands. It is not entirely understood how the electric currents of an iontophoresis machine work, but it is believed the iontophoresis device encourages skin thickening, alters nerve transmissions, and reduces sweat gland activity.

Iontophoresis can be performed in a dermatology office or at home with tap water iontophoresis. There are few adverse effects associated with these hyperhidrosis treatments, and many individuals report improved quality of life with both the professional and home-use options. Other modalities used in the treatment of hyperhidrosis include anticholinergics, antiperspirants, Botox®, and surgical treatments like ETS.

What cosmetic concerns does iontophoresis treat?

  1. Excessive Sweating: Iontophoresis passes electric currents through the body to thicken the outer skin layer, disrupt nerve transmission, and reduce sweat gland production.

Who is the ideal candidate for iontophoresis?

The ideal candidate for iontophoresis is seeking a minimally invasive treatment for axillary hyperhidrosis, palmar hyperhidrosis, or plantar hyperhidrosis. Iontophoresis is not recommended for pregnant women, those with a cardiac pacemaker medical device, metal implants, or those with certain sensitive skin types.

What is the average recovery associated with iontophoresis?

There is little to no recovery associated with iontophoresis treatments. Some patients experience mild skin irritation or sensitivity immediately following treatments. Treatments are generally spaced a few days to weeks apart.

What are the potential side effects of iontophoresis?

Possible side effects of iontophoresis include blister formation, bruising, altered nerve sensation, thickening of skin at the treated areas, and itchiness.

What can someone expect from the results of iontophoresis?

The results of iontophoresis treatments will evolve gradually over a series of treatments over a few weeks. Maintenance therapy will then be needed every few weeks to maintain the results.

What is the average cost of iontophoresis?

The average cost of iontophoresis is $100 to $150. The actual cost of iontophoresis will vary by location, healthcare provider, and individual candidate needs.


  • Non-invasive
  • Relatively Inexpensive


  • Maintenance Required
  • Temporary Results

Invasiveness Score


Invasiveness is graded based on factors such as anesthesia practices, incisions, and recovery notes common to this procedure.

What to Expect

Iontophoresis therapy is a noninvasive electric treatment. Here is a general guide for what to expect before, during, and after Iontophoresis:

The Takeaway

Iontophoresis is a noninvasive professional or at-home treatment option for palmar, plantar, and axillary hyperhidrosis.

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Source List


AEDIT uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

  1. Sharon Orrange, MD, MPH Is Your Medication Making You Sweat? 10 Drugs That Cause Excessive Sweating as a Side Effect


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