Botox for Hyperhidrosis

Botox has the ability to temporarily block the secretion of the chemical that is responsible for stimulating the body's sweat glands. By interrupting this chemical messenger, the botulinum toxin inhibits sweating in the area where it has been injected. Common areas for botox injections for hyperhidrosis include the underarms and palms of the hands.

Botox for Hyperhidrosis Overview - Everything You Need to Know

The Skinny

Botox for Hyperhidrosis
avg. recovery
1 days
$1000 - $1500

About the Procedure

Last Updated: 09.17.2021

Botox injections are commonly used to inhibit muscle movement to prevent wrinkles and fines lines from forming however, the naturally derived toxin can also be used to temporarily chemo-denervate the eccrine glands involved in hyperhidrosis. Typically, 50-100 units of Botox will be injected into each underarm for treatment. The cumulative dose of botox should not exceed 360 units in a three-month period, as recommended by the FDA. In order to determine the area to be injected, a starch iodine test will be administered to determine the location of the sweat glands. Alternatively, areas may be marked for injection based off of the hair-bearing area. Approximately 40 evenly-distributed injection sites are placed in each underarm, with the injection sites being 8 mm apart. Once inserted, the syringe will deposit approximately 0.05 mL of the solution subdermally, after which it is withdrawn. While only FDA approved for treatment of overactive sweat glands in the axilla, it is common for botox to be injected into the palms of the hands and soles of the feet for hyperhidrosis treatment as well.

The goal of botox injections for hyperhidrosis is to decrease or eliminate excessive sweating in the underarms.


Botox for Hyperhidrosis addresses concerns such as:

Recovery Notes

Intense exercise should be avoided for a few hours after botox treatment for hyperhidrosis. Reduction in underarm sweating will be noticeable within several weeks. In the event that some sweat glands are missed in the initial treatment, some sweating from untreated areas may occur.

Ideal Candidate

The ideal candidate for botox injections for hyperhidrosis experiences severe underarm sweating that impacts quality of life.

Not Recommended For

Botox injections are not recommended for patients under the age of 18.

Side Effects

Side effects of botox may include loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks after treatment. These side effects are temporary however it is best to call your provider should you experience adverse reactions for more than 24-48 hours.


  • no downtime
  • quick results


  • temporary
  • multiple treatments

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