Concerns with Nasolabial Folds - 100

Nasolabial Folds

All people develop nasolabial folds with age. They cause no medical problems but some people are concerned about their effects on physical appearance. Various outpatient treatment options are available to safely enhance the appearance of unsightly smile lines and other deep facial wrinkles.

The Skinny

Content Reviewed by AEDIT Medical Advisory Board

What are Nasolabial Folds?

The nasolabial folds are indented lines in the skin that extend from the edges of the nose to the outer corners of the mouth. They are more pronounced when smiling or making certain other facial expressions which is the reason they are often called “laugh lines” or “smile lines”. They are normal parts of the human face and often deepen over time. Newborn babies and some people with facial paralysis are the only people who do not have nasolabial folds.

Anatomically, smile lines are comprised of facial muscle tissues and dense groupings of fibrous tissue. Over time, these tissues tend to become more closely compacted. The skin typically thins or sags with aging, making the nasolabial folds more noticeable. This affects the appearance of the upper lip, midface, and cheek area.

Laugh lines often deepen over time because of repetitive smiling. There is no medical reason to have them modified. However, some people are bothered by the appearance of theirs and feel the need to have them treated. This is especially true in those who also have other deeper wrinkles on their faces.

Many people also develop “marionette lines” as their nasolabial folds deepen. These lines extend from the corners of the mouth down to circumvent the chin. They terminate at the pre-jowl sulcus, which are the hollow areas on each side of the chin that form the jowl. Combined smile and marionette lines can give the lower face a saddened look.

A skilled plastic surgeon will be able to determine the best course of nasolabial fold treatment. Every patient has various personal factors that dictate the best solution. What works very well for one may not be suitable for another. Various facial rejuvenation procedures are available that can help to restore a more youthful appearance.

The Specifics

How to Treat Smile and Laugh Lines: Fillers, Surgery, and At Home Treatment

Nasolabial folds are not medical issues. However, they contribute to cosmetic issues in some people when they are very deep or otherwise overly pronounced. Because of that, various treatment procedures and techniques have been developed to reduce their appearance or eliminate them.

Safe and effective nasolabial fold treatments include:

  • Surgery
  • Chemical Peels
  • Microdermabrasion
  • Dermal Fillers & Injectables
  • Thread Lift
  • Laser Resurfacing

Nasolabial Fold Surgery Plastic surgeons typically use a surgical procedure called subcision to lessen the appearance of deep nasolabial folds. A needle is used to break apart dense tissue pockets, and then, they are positioned to reduce the depth of the folds. This leaves the smile lines and surrounding area with a more youthful appearance.

A more aggressive surgical approach called excision can be used in more extreme cases. Direct excision involves the surgical removal of tissue and skin to reshape the area of concern. The technique is more intense but can also yield more dramatic results than the subcision.

Chemical Peels This is a skin resurfacing procedure that involves using a chemical solution to exfoliate the skin’s outer layers to enhance its appearance. This treatment encourages skin tightening by stimulating collagen production and cell turnover, resulting in a smoother and brighter skin appearance.

Light, medium, and deep chemical peels are available. However, even deep chemical peels may not be enough to improve the appearance of deep laugh lines. Discuss the possibilities with a dermatologist or plastic surgeon to learn what’s best for you.

Dermal Fillers & Injectables Various dermal fillers can be used to enhance the aesthetics of deep smile lines. Some of the hyaluronic acid filler treatments that are approved by the FDA are Juvederm®, Perlane®, Radiesse®, Restylane®, Sculptra®, and Voluma®.

These dermal fillers are placed just beneath the surface of the skin to add volume in areas where a fat pad has degraded with age, or where deep wrinkles and skin folds have become concerning. They plump up the skin and thereby enhance aesthetics.

Dermal filler placement is a quick, comfortable outpatient procedure. For treating nasolabial fold concerns, the filler is placed either directly into the fold to add volume, or into the upper cheek to detract from the fold’s noticeability. Neuromodulators, like Botox®, can also be used to reduce the appearance of nasolabial folds when expertly placed within the midface while not affect the movement of the upper lip.

Dermal fillers will not make unsightly nasolabial folds disappear completely. However, they can significantly enhance their appearance. Note that dermal fillers are temporary solutions. How long they last in any one patient depends on various patient-specific factors. A dermatologist or plastic surgeon can determine the best treatment for you.

Thread Lifts A thread lift is a procedure that suspends some of the facial skin with temporary sutures instead of excising the extra tissue. It can produce skin tightening effects and significantly improve the appearance of the nasolabial folds. The procedure also stimulates collagen production which is integral to maintaining skin elasticity with aging.

Laser Resurfacing Laser skin resurfacing helps to reduce the appearance of smile lines, deep wrinkles, and other facial concerns. It removes superficial layers of the skin to help correct minor blemishes and flaws. This precise and safe technique also stimulates collagen and new skin cell production.

How to Prevent Nasolabial Folds

Nasolabial folds are natural parts of the facial anatomy. They are harmless and do not require medical treatment. Even small children have them when smiling.

There is no known way to prevent nasolabial folds from developing. Some preliminary research suggests that those who are concerned about developing deeper nasolabial folds as they age should be sure to wear sunscreen when they plan on being outside. Slowing down the damage to skin cells from sun exposure might help to reduce the progression of laugh lines with age.

Rapid weight loss can also cause a thinning of facial fat tissue and make the nasolabial folds more noticeable. Smoking also contributes to facial wrinkles in general; another reason to avoid it.

Taking a collagen or gelatin supplement might help to prevent the deepening of laugh lines with age by maintaining the integrity of the connective tissues that keep the skin tight. Eating a healthy diet is also important for ensuring an adequate intake of other important nutrients. Adequate water intake is also crucial for healthy skin.

Facial Exercises Doctors are working on developing new nonsurgical methods for treating deep nasolabial folds. Some believe that routinely performing exercises for the facial muscles might help to reduce their appearance.

The idea is that the facial muscles are like other muscles and respond to physical exertion. Just as a toned stomach is less likely to sag, facial muscles that are worked will also maintain more structural integrity.

While frequent and intense smiling is linked to causing nasolabial folds, nobody would recommend trying not to smile to avoid them. Smiling and laughing are very important for all people, helping to balance emotions and maintain long-term mental health.

In theory, exercising the face to make muscle movements in the opposite direction they do when smiling can be beneficial. Some of the movements recommended are:

  • Intensely pout the lips for 20 seconds and repeat 4 times
  • Pucker the lips toward the ceiling, hold for 20 seconds, and repeat 4 times
  • Stretch the corners of the mouth outward, hold for 20 seconds, and repeat 4 times

There has not been any reliable research that supports using these exercises to improve the appearance of nasolabial folds. However, in theory, they may help to keep the facial muscles toned and the skin tight with age.

The Takeaway

Preventing and Treating Nasolabial Folds

There are various treatments to reduce nasolabial folds, and some will be better suited for you than others. Everyone has unique facial characteristics and no two people will respond the same to any procedure or technique. Seek professional medical advice about the best treatment options for improving the appearance of your nasolabial fold lines.

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Source List


AEDIT uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

  1. Samad Rezaee Khiabanlo Innovative techniques for thread lifting of face and neck; 2019-12-02
  2. American Academy of Dermatology Many Ways to Firm Sagging Skin
  3. The American Board of Cosmetic Surgery Skin Tightening
  4. Uwe Wollina Treatment of Facial Skin Laxity by a New Monopolar Radiofrequency Device


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