Mesotherapy, also referred to as injection lipolysis or lipodissolve, is a method of fat reduction that consists of an individualized injection of vitamins, vasodilators, nonsteroidal anti-inflammatory medications, enzymes, nutrients, antibiotics, and hormones. The injection is purported to destroy fat cells for a slimmer body contour. Mesotherapy is a controversial procedure and is not approved by the FDA.

Mesotherapy Overview - Everything You Need to Know

The Skinny

avg. recovery
0 days
$250 - $12000

About the Procedure

Last Updated: 09.18.2021

Mesotherapy injections are touted as a noninvasive method for reducing fatty deposits in the stomach, thighs, neck, arms, back, and anywhere else on the body with unwanted bulges. The exact ingredients used in a mesotherapy injection are not standardized and vary from provider to provider, as the injections are customized to the needs of the patient. Typically, the injection will be comprised of phosphatidylcholine, which is a soybean extract, as well as deoxycholate, which is a bile derivative. Phosphatidylcholine is FDA approved to break down fat found in blood that may interfere with heart health, but is not approved for any other use. Other common additives to a mesotherapy injection include vasodilators (to improve blood flow to the treatment area), anti-inflammatory medicines (to reduce any swelling), antibiotics, nutrients, and enzymes. Although mesotherapy has been practiced for decades in Europe, there have been no thorough scientific studies in regards to the effectiveness of the treatment. The American Society for Plastic Surgeons warns that patients should be wary of the treatment until further data is collected about the safety and efficacy of the procedure. Studies are being conducted to better understand and regulate the treatment. Before injection, the practitioner will evaluate the patient in order to create a customized cocktail for injection which can include a number of ingredients. The treatment area will be cleansed and the injection will be placed in the subcutaneous fat layer. Several session are needed depending on the severity of the issue being treated. Patients should expect to have 1-15 sessions spaced 1-2 weeks apart with upkeep treatments every 6 months.

The primary goal of mesotherapy is to dissolve fat deposits for improved body contours. Mesotherapy is also used for pain therapy, cellulite treatment, hair loss, amongst other indications.


Mesotherapy addresses concerns such as:

Recovery Notes

Most patients are able to return to normal activity immediately after treatment however are advised to avoid strenuous exercise for 2 days. Do not take anti-inflammatory medications for 48 hours after treatment as the body’s natural response to inflammation is necessary for the treatment to work.

Ideal Candidate

The ideal candidate for mesotherapy has stubborn, exercise and diet resistant fatty deposits and does not want an invasive treatment. Other candidates for mesotherapy may be looking to treat cellulite, hair loss, or body pains.

Not Recommended For

Mesotherapy is not recommended for patients with an unstable or unhealthy weight, who are pregnant or breast feeding, who are taking anticoagulants or cardiac drugs, or with chronic conditions such as diabetes or liver and kidney disorders.

Side Effects

Side effects from mesotherapy treatment may include redness, stinging, and a burning sensation which can last up to 2 hours after injection. Swelling and bruising typically peaks 6-72 hours after treatment. Some patients will experience nodules or hardening at the injection site.


  • can treat a variety of indications
  • has been used as a treatment in Europe for decades


  • not FDA approved
  • no standardized method of treatment
  • unpredictable results

We’ve done the homework.
Your trusted source for aesthetic solutions, "try it on" now.

Download our 3D Aesthetic Simulator App
App store icon