Semi-Permanent Lip Fillers

Semi-permanent lip fillers are lip augmentation injectable compounds that are longer lasting than temporary lip fillers like Juvederm, CosmoDerm, and Zyplast. Popular options include Sculptra, Bellafill, Aquamid, and Radiesse. Semi-permanent lip fillers stimulate the production of natural collagen and typically last for more than a year.

Semi-Permanent Lip Fillers Overview - Everything You Need to Know

The Skinny

Semi-Permanent Lip Fillers
avg. recovery
5 days
$600 - $800

About the Procedure

Last Updated: 07.28.2021

Semi-permanent lip fillers give patients an immediate improvement in fullness but show best results several weeks after the initial injection. This is because semi-permanent fillers rely on encouraging the patient's own natural collagen production to increase lip volume. A local or topical anesthetic is used during the administration of semi-permanent lip filler compounds. Using these fillers to add volume to the lips typically requires 1-2 separate sessions. Since this specific type of filler relies on stimulating the patient's own collagen production, it is common for patients to have sessions spaced out over several weeks or months to ensure the lips are not "over-filled". Most patients report only mild discomfort. Some tightness, swelling, and mild pain may be experienced for 1-3 days after the procedure. The fillers are administered with blunt-tipped cannula needles that are inserted through stab incisions made in the corners of the mouth. These robust, long-lasting lip augmentations cost up to $800 per treatment depending on the type of filler used and the desired fullness.

Plump lips are often desired for a more youthful appearance. Lip enhancements with semi-permanent lip fillers seek to fill thin lips.


Semi-Permanent Lip Fillers addresses concerns such as:

Recovery Notes

Redness and swelling is common for the first 24 hours after semi-permanent lip fillers and can be alleviated with the use of cool compresses. Avoid massaging or manipulating the injected areas. Do not engage in strenuous activities for at least 6 hours. Sleep with the head in an elevated position to further reduce any residual swelling.

Ideal Candidate

The ideal candidate for lip fillers does not require a surgical procedure and only requires subtle refinement of lip fullness, projection and eversion.

Not Recommended For

Lip fillers are not recommended for candidates who are pregnant or breastfeeding.

Side Effects

Side effects from lip fillers can include pain, bruising, asymmetry or nodule formation. There is always the risk that filler alone is inadequate to augment the lips and those candidates should be considered for surgery. The serious complication of injectable fillers is intravascular injection leading to skin necrosis. Immediate regional blanching, a reticulate, purple discoloration of the skin, or significant pain following treatment may indicate impending tissue necrosis.


  • no surgery
  • promotes collagen growth


  • temporary
  • multiple treatments
  • asymmetry
  • higher incidence of nodules

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